Chemical Biology Faculty

Learn more about this group by contacting Dr. Kojo Mensa-Wilmot (mensawil@uga.edu) or visiting the Chemical Biology website.

Chemical Biology is an interdisciplinary field of study that bridges the traditional fields of chemistry and biology, applying chemical methods to problems in biology. Often, the tools used are compounds produced through synthetic chemistry that are designed with guidance from structural biology to manipulate physiological processes, providing insight as to how these processes work and sometimes leading to the creation of new function.

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Photo of Michael W. W. Adams
Michael W. W. Adams
Distinguished Research Professor Biochemistry & Molecular Biology

Functional and structural genomics, metabolism and enzymology of organisms that grow near 100C.

Photo of Fikri Avci
Fikri Avci
Assistant Professor Biochemistry & Molecular Biology

Mechanisms of immune activation by carbohydrate antigens; design and development of knowledge-based vaccines and therapeutics against pathogens and cancers.

Photo of David L. Blum
David L. Blum
Director, Bioexpression & Fermentation Facility Biochemistry & Molecular Biology

Protein expression, development of commercially relevant monoclonal antibodies.

Photo of Brian Cummings
Brian Cummings
Associate Professor Neuroscience; Pharmaceutical & Biomedical Sciences; Toxicology

Molecular toxicology, cell signaling, prostate cancer, anti-cancer, kidney.

Photo of Steve Dalton
Steve Dalton
Professor Biochemistry & Molecular Biology

Stem cell biology, development of cell therapies for type 1 diabetes and cardiovascular disease. Pluripotent stem cells in early development and induced pluripotent stem cells- cell reprogramming.

Photo of Roberto Docampo
Roberto Docampo
Professor Cellular Biology

Cellular and molecular biology of acidocalcisomes; the role of polyphosphate in trypanosomatids.

Photo of Diana M. Downs
Diana M. Downs
Professor Microbiology

Bacterial physiology and metabolic integration using biochemical, genetic and metabolomics approaches.

Photo of Arthur S. Edison
Arthur S. Edison
Professor Biochemistry & Molecular Biology; Genetics

Metabolomics and systems biology of Caenorhabditis elegans using NMR, mass spec, and computational approaches.

Photo of Jorge C. Escalante-Semerena
Jorge C. Escalante-Semerena
UGA Foundation Distinguished Professor Microbiology

Prokaryotic metabolism and physiology with emphasis on protein acetylation, toxic metabolites, and complex metabolic pathway analysis, integration.

Photo of Shelley Hooks
Shelley Hooks
Associate Professor Neuroscience; Pharmaceutical & Biomedical Sciences

G-protein coupled receptors, molecular pharmacology, signal transduction, ovarian cancer, neural stem cells.

Photo of Natarajan Kannan
Natarajan Kannan
Associate Professor Biochemistry & Molecular Biology; Bioinformatics

Evolutionary systems biology; protein kinase signaling in plants, pathogens and microbes.

Photo of Eileen Kennedy
Eileen Kennedy
Associate Professor Pharmaceutical & Biomedical Sciences

Chemical biology, kinase signaling, cancer, signal transduction, drug discovery.

Photo of Edward T. Kipreos
Edward T. Kipreos
Professor Cellular Biology

Regulation of the cell cycle; ubiquitin-mediated proteolysis and development.

Photo of Dennis Kyle
Dennis Kyle
Professor Cellular Biology & Infectious Diseases

The discovery and development of new drugs to prevent or treat malaria and leishmaniasis. Elucidating mechanism(s) of resistance and discovering new drug treatment regimens, combinations, or strategies to overcome resistance.

Photo of William N. Lanzilotta
William N. Lanzilotta
Associate Professor Biochemistry & Molecular Biology

The mechanisms of metalloproteins involved in radical generation, oxidative stress protection, as well as heme synthesis, sensing, aquisition and transport.

Photo of George Majetich
George Majetich
Professor Chemistry
Photo of Amy Medlock
Amy Medlock
Assistant Professor Biochemistry & Molecular Biology

Understanding intracellular and intercellular heme transport.

Photo of Kojo Mensa-Wilmot
Kojo Mensa-Wilmot
Professor Cellular Biology

Cell Signaling, Organelle Biogenesis, and Drug Discovery in Trypanosomes.

Photo of Cory Momany
Cory Momany
Associate Professor Pharmaceutical & Biomedical Sciences

Antibiotic drug discovery targeting RNA polymerase regulation; X-ray crystallography of non-coding RNA and prokaryotic transcriptional regulators

Photo of Kelley Moremen
Kelley Moremen
Professor Biochemistry & Molecular Biology

Biochemistry, molecular, and structural biology of mammalian glycoprotein biosynthesis and catabolism.

Photo of Silvia Moreno
Silvia Moreno
Professor Cellular Biology

Metabolism and drug development against protozoan parasites. Calcium signaling and storage in Toxoplasma gondii.

Photo of Mandi Murph
Mandi Murph
Associate Professor Pharmaceutical & Biomedical Sciences

Chemical inhibitors of cancer, chemoresistance, tumor biology and animal models.

Photo of Ron Orlando
Ron Orlando
Associate Professor Biochemistry & Molecular Biology

Solving biological/biomedical problems with mass spectrometry.

Photo of Robert S. Phillips
Robert S. Phillips
Professor Chemistry; Biochemistry and Molecular Biology

Enzymes involved in amino acid, especially tryptophan, metabolism which may be drug targets for cancer, hypertension and neurodegenerative diseases.

Photo of Michael “Hawkeye” Pierce
Michael “Hawkeye” Pierce
Distinguished Research Professor, Director UGA Cancer Center Biochemistry & Molecular Biology

Glycosyltransferase regulation of tumor cell adhesion and invasion; structure/function of lectins.

Photo of Vladimir Popik
Vladimir Popik
Professor of Chemistry Chemistry

Development of biorothogonal protein modification techniques, novel caging groups, and photoactivatable antitumor antibiotics

Photo of James H. Prestegard
James H. Prestegard
Professor Emeritus, Georgia Research Alliance Eminent Scholar Biochemistry & Molecular Biology

Application of Nuclear Magnetic Resonance Spectroscopy to the characterization of biologically important systems.

Photo of Arthur Roberts
Arthur Roberts
Assistant Professor Pharmaceutical & Biomedical Sciences; Toxciology

Development of high-throughput structural biology tools, biophysical methods, NMR, and computer-aided drug-design to investigate drug-protein interactions and human disease.

Photo of John Rose
John Rose
Associate Professor Biochemistry & Molecular Biology

X-ray structural biology, the mitochondrial inner membrane space transport system, structure based vaccine and therapeutic design, improved/automated methods for synchrotron SAD data collection and structure determination.

Photo of Walter K. Schmidt Jr.
Walter K. Schmidt Jr.
Associate Professor, Georgia Cancer Coalition Scholar Biochemistry & Molecular Biology

Molecular cell biology and biochemistry of proteases associated with isoprenylated protein maturation and amyloidogenic peptide degradation; cancer; Alzheimer’s disease.

Photo of Anne Summers
Anne Summers
Professor Microbiology; Toxciology

Environmental stress biology, using biochemical, biophysical, and ‘omics approaches to define the roles of toxic metal exposure in chronic and infectious diseases.

Photo of M. Stephen Trent
M. Stephen Trent
Distinguished Professor Infectious Diseases

Characterizing the assembly of bacterial surface structures, Development of vaccines for viral and bacterial pathogens, Systems approaches to understanding microbial diseases

Photo of C.J. Tsai
C.J. Tsai
Professor, Georgia Research Alliance Eminent Scholar Bioinformatics; Genetics

Growth-defense tradeoff, phenylpropanoid metabolism and carbon allocation, gene family evolution and functional diversification, alternative splicing and gene duplication.

Photo of Bi-Cheng Wang
Bi-Cheng Wang
Professor, Georgia Research Alliance Eminent Scholar Biochemistry & Molecular Biology

Structure-function studies by X-ray diffraction, transcription proteins, structural genomics, phasing methods.

Photo of Wendy Watford
Wendy Watford
Assistant Professor Infectious Diseases

Regulation of host defense and tolerance by Stat transcription factors.

Photo of Lance Wells
Lance Wells
Associate Professor, Georgia Cancer Coalition Scholar Biochemistry & Molecular Biology

Role of post-translational modifications, primarily O-glycosylation, in human diseases including type II diabetes, cancer, and congenital muscular dystrophy.

Photo of Christopher M. West
Christopher M. West
Professor Biochemistry & Molecular Biology

Oxygen- and glycosylation-dependent regulation of polyubiquitin ligases in Dictyostelium and Toxoplasma gondii; Glycobiology of protozoa

Photo of William Whitman
William Whitman
Professor Bioinformatics; Microbiology

Evolution, ecology, physiology of methane-producing archaeon Methanococcus, the marine alpha proteobacteria, and soil bacteria.

Photo of Zachary A. Wood
Zachary A. Wood
Associate Professor Biochemistry & Molecular Biology

X-ray crystallographic and biochemical studies of nucleotide sugar metabolism.

Photo of William S. York
William S. York
Professor Biochemistry & Molecular Biology

Structure, function, and assembly of plant cell walls; Bioinformatics for glycomics and glycobiology.

Photo of Jason Zastre
Jason Zastre
Associate Professor Pharmaceutical & Biomedical Sciences; Toxciology

Transport, micronutrient, hypoxia, cancer.

Photo of Y. George Zheng
Y. George Zheng
Associate Professor, Georgia Cancer Coalition Distinguished Scholar Pharmaceutical & Biomedical Sciences

Chemical biology, epigenetics and chromatin, medicinal chemistry, drug discovery, organic synthesis, bioorganic chemistry, posttranslational modification, molecular biology, biochemistry, enzymology, and bioinformatics.

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