Structural Biology

Learn more about this group by contacting
Dr. John Rose
 (jprose@uga.edu) or
Dr. Robert Woods (rwoods@ccrc.uga.edu).

Structural Biology are interdisciplinary research areas that routinely integrate advanced computing techniques (dynamics, molecular modelling, simulations) and specialized physical methods (crystallography, nuclear magnetic resonance, spectroscopy) to solve exciting questions in biological systems.  The disciplines often work at the molecular level and utilize fundamental principles derived from mathematics, chemistry, and physics.

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Photo of David L. Blum
David L. Blum
Director, Bioexpression & Fermentation Facility Biochemistry & Molecular Biology

Protein expression, development of commercially relevant monoclonal antibodies.

Photo of Arthur S. Edison
Arthur S. Edison
Professor Biochemistry & Molecular Biology; Genetics

Structural analysis and characterization of glycosaminoglycans using mass spectrometryStructural analysis and characterization of glycosaminoglycans using mass spectrometry Metabolomics and systems biology of Caenorhabditis elegans using NMR, mass spec, and computational approaches.

 

Photo of Natarajan Kannan
Natarajan Kannan
Associate Professor Biochemistry & Molecular Biology; Bioinformatics

Evolutionary systems biology; protein kinase signaling in plants, pathogens and microbes.

Photo of William N. Lanzilotta
William N. Lanzilotta
Associate Professor Biochemistry & Molecular Biology

The mechanisms of metalloproteins involved in radical generation, oxidative stress protection, as well as heme synthesis, sensing, aquisition and transport.

Photo of Amy Medlock
Amy Medlock
Assistant Professor Biochemistry & Molecular Biology

Understanding intracellular and intercellular heme transport.

Photo of Cory Momany
Cory Momany
Associate Professor Pharmaceutical & Biomedical Sciences

Antibiotic drug discovery targeting RNA polymerase regulation; X-ray crystallography of non-coding RNA and prokaryotic transcriptional regulators

Photo of Kelley Moremen
Kelley Moremen
Professor Biochemistry & Molecular Biology

Biochemistry, molecular, and structural biology of mammalian glycoprotein biosynthesis and catabolism.

Photo of Scott Pegan
Scott Pegan
Associate Professor Pharmaceutical & Biomedical Sciences

Antiviral and nerve agent poisoning therapeutic discovery, assay development, enzymology, structural biology, regulation of innate immune responses

Photo of Robert S. Phillips
Robert S. Phillips
Professor Chemistry; Biochemistry and Molecular Biology

Enzymes involved in amino acid, especially tryptophan, metabolism which may be drug targets for cancer, hypertension and neurodegenerative diseases.

Photo of James H. Prestegard
James H. Prestegard
Professor Emeritus, Georgia Research Alliance Eminent Scholar Biochemistry & Molecular Biology

Application of Nuclear Magnetic Resonance Spectroscopy to the characterization of biologically important systems.

Photo of Arthur Roberts
Arthur Roberts
Assistant Professor Pharmaceutical & Biomedical Sciences; Toxciology

Development of high-throughput structural biology tools, biophysical methods, NMR, and computer-aided drug-design to investigate drug-protein interactions and human disease.

Photo of John Rose
John Rose
Associate Professor Biochemistry & Molecular Biology

X-ray structural biology, the mitochondrial inner membrane space transport system, structure based vaccine and therapeutic design, improved/automated methods for synchrotron SAD data collection and structure determination.

Photo of Jeffrey Urbauer
Jeffrey Urbauer
Associate Professor Biochemistry & Molecular Biology; Chemistry

Structural biology of transcription regulation, steroid hormone activation and breast cancer.

Photo of Bi-Cheng Wang
Bi-Cheng Wang
Professor, Georgia Research Alliance Eminent Scholar Biochemistry & Molecular Biology

Structure-function studies by X-ray diffraction, transcription proteins, structural genomics, phasing methods.

Photo of Christopher M. West
Christopher M. West
Professor Biochemistry & Molecular Biology

Oxygen- and glycosylation-dependent regulation of polyubiquitin ligases in Dictyostelium and Toxoplasma gondii; Glycobiology of protozoa

Photo of Zachary A. Wood
Zachary A. Wood
Associate Professor Biochemistry & Molecular Biology

X-ray crystallographic and biochemical studies of nucleotide sugar metabolism.

Photo of Robert J. Woods
Robert J. Woods
Professor Biochemistry & Molecular Biology

Immunological carbohydrate-protein interactions studied by computational simulation and experimental methods.

Photo of Ying Xu
Ying Xu
Professor, Georgia Research Alliance Eminent Scholar Biochemistry & Molecular Biology; Bioinformatics

Cancer Computational and Systems Biology, Computational Methods for Protein Structure Prediction and Modeling.

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