University of Georgia
We use the advanced genetic mouse models to study the molecular and cellular mechanisms underlying
several diseases: obesity, diabetics, muscle and heart diseases.
Nutritional Genomics; Human Genetics; Population and Quantitative Genomics;
Gene-Diet Interaction during human evolution and in metabolic diseases;
Defining the spatiotemporal regulation of kinase pathways and the regulation of GPCR induced
inflammation and proangiogenic signaling, for the development of therapeutic agents.
Stroke is the second leading cause of death worldwide. We explore the potential of neural stem cells
and other regenerative therapies to recover lost and damaged brain tissue. We utilize a novel
pig ischemic stroke model in conjunction with magnetic resonance imaging, cognitive,
motor function testing and histology.
Neurocognition of creativity & imagination – reality/fiction distinction, self/social cognition, mental time travel, semantic cognition, aesthetics
Molecular mechanism of embryo implantation. Endocrine disruptors on puberty and early pregnancy.
Neurotoxic agents that alter synaptic transmission. The actions of toxins such as
the Clostridial neurotoxins (Botulinum and Tetanus) at the mammalian neuromuscular junction.
Effects of pathological stress on cells of the peripheral nervous system and the adrenal gland. In vitro disease modeling using human pluripotent stem cells.
