Zhao, Shaying
Shaying Zhao
Professor
Biochemistry & Molecular Biology; Bioinformatics
Cancer genomics; human junk DNA; genomic instability.
Cancer genomics; human junk DNA; genomic instability.
Immunological carbohydrate-protein interactions studied by computational simulation and experimental methods.
X-ray crystallographic and biochemical studies of nucleotide sugar metabolism.
Role of protein glycosylation in intellectual disability, congenital muscular dystrophy, cancer, and viral infection.
Structure-function studies by X-ray diffraction, transcription proteins,
structural genomics, phasing methods.
Structural biology of transcription regulation, steroid hormone activation and breast cancer.
Mechanisms that regulate the expression, function, and structure of tissue-specific glycans.
We study CRISPR-Cas immune systems that protect prokaryotes from viruses and provide
powerful research tools for important biotechnology and biomedical applications.
Molecular cell biology and biochemistry of proteases associated with isoprenylated protein
maturation and amyloidogenic peptide degradation; cancer; Alzheimer’s disease.
Molecular and biochemical parasitology: DNA modification, homologous recombination
and the regulation of antigenic variation in Trypanosoma brucei.