University of Georgia
Environmental stress biology, using biochemical, biophysical, and ‘omics approaches to define the roles of toxic metal exposure in chronic and infectious diseases.
Molecular cell biology and biochemistry of proteases associated with isoprenylated protein maturation and amyloidogenic peptide degradation; cancer; Alzheimer’s disease.
X-ray structural biology, the mitochondrial inner membrane space transport system, structure based vaccine and therapeutic design, improved/automated methods for synchrotron SAD data collection and structure determination.
Solving biological/biomedical problems with mass spectrometry.
Metabolism and drug development against protozoan parasites.
Calcium signaling and storage in Toxoplasma gondii.
Biochemistry, molecular, and structural biology of mammalian glycoprotein biosynthesis and catabolism.
X-ray crystallography of macromolecules, prokaryotic transcriptional regulators.
Understanding intracellular and intercellular heme transport.
The mechanisms of metalloproteins involved in radical generation, oxidative stress protection, as well as heme synthesis, sensing, aquisition and transport.
Regulation of the cell cycle; ubiquitin-mediated proteolysis and development.
