Wang, Yifan
Yifan Wang
Assistant Professor
Chemistry
Catalytic mechanisms and structure-function correlations of metalloenzymes; biomedically essential oxygenases
Catalytic mechanisms and structure-function correlations of metalloenzymes; biomedically essential oxygenases
Organic and medicinal chemistry; carbohydrate chemistry; glycomimetics; drug design and development with emphasis on multi-drug resistant infectious diseases
Lipidomic and metabolomic analyses of antimicrobial resistant pathogens using ion mobility and mass spectrometry
Development of synthetic organic methodologies to produce active pharmaceutical ingredients. Microwave-promoted synthesis of bioactive amines.
Development of biorothogonal protein modification techniques, novel caging groups, and photoactivatable antitumor antibiotics.
Enzymes involved in amino acid, especially tryptophan, metabolism which may be drug targets for cancer, hypertension and neurodegenerative diseases.
Our research is focused on functional polymer interfaces. We are
currently developing methodologies and platforms that can be used
to study biological lubrication, patterning of cellular components in
two and 3 dimensions, patterning of glycosaminoglycans to study
nerve regeneration, 3D printing of biodegradable scaffolds, and antimicrobial coatings.
Structural analysis and characterization of glycosaminoglycans using mass spectrometry