University of Georgia
All facets of host-parasite interactions during malaria, ranging from molecular pathogenesis to malaria immunology to transmission
The Huet Lab will use metabolomics and CRISPR-based approaches to understand the mitochondrial and organellar biology of a class of protozoan parasites, the apicomplexans.
Basic immunology of the liver and blood stages of malaria
Metabolomic approaches applied to drug target selection and validation in human pathogens; discovery and development of new chemotherapeutic interventions.
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The discovery and development of new drugs to prevent or treat malaria and diseases caused by brain-eating amoebae. Elucidating mechanism(s) of resistance and discovering new drug treatment regimens, combinations, or strategies to overcome resistance.
Toxoplasma’s Strategies to Manipulate Host Immunity
Oxygen- and glycosylation-dependent regulation of polyubiquitin ligases in Dictyostelium and Toxoplasma gondii; Glycobiology of protozoa.
Molecular and cellular biology of the human malaria parasite, Plasmodium falciparum.
Characterization of adhesion proteins which mediate host-parasite interactions in Plasmodium falciparum.
Mechanisms of immunity and disease in Trypanosoma cruzi infection (Chagas Disease); Basic and applied biology of T. cruzi.
