University of Georgia
Targeted therapy and cancer chemoprevention; preclinical animal models; cancer immunotherapy; tumor microenvironment and exosomal microRNAs; biomarker of tumor metastasis.
Our work focuses on understanding the regulation of cell envelope biosynthesis in bacteria using genetic, biochemical, and cell biological approaches.
Our lab seeks to uncover novel regulatory mechanisms of biofilm formation to undermine bacterial survival in chronic infections.
High throughput genetics to better understand evolution of fungal pathogens and drive antifungal drug discovery.
Research focuses on cellular and molecular mechanisms of neurodegeneration, identifying novel immunomodulatory drugs, discovering biomarkers for diabetes, Parkinson’s and Alzheimer’s diseases related dementia.
Research focuses on cellular and molecular mechanisms of neurodegeneration, identifying novel druggable targets, discovering prodromal biomarkers and novel reengineered gut microbiome based therapeutics for treatment of neurological disorders such as Parkinson’s and Alzheimer’s diseases and related dementia.
Translational research in biomaterials (antifouling, antiplatelet, antibacterial, and antiviral) for tissue engineering and medical device applications
Multi-drug resistance(MDR) causes most cancer deaths(Nat. Rev. Cancer 2018, 18, 452). We use organic chemistry, cell biology and data-science to overcome MDR.
Molecular and cellular mechanisms of brain tumors; oncohistone mutations; human ES cell-based tumor modeling; tumor heterogeneity and evolution
Organic and medicinal chemistry; carbohydrate chemistry; glycomimetics; drug design and development with emphasis on multi-drug resistant infectious diseases
