University of Georgia
The research in Dr. Li’s laboratory combines biochemistry, genetics, adductomics and computational approaches to investigate effects of epigenetics and spatial genome organization on environmental carcinogen-induced DNA damage formation, DNA repair, mutagenesis, and carcinogenesis.
Meiotic chromosome biology using Drosophila as a model system.
Molecular and cellular mechanisms of brain tumors; oncohistone mutations; human ES cell-based tumor modeling; tumor heterogeneity and evolution
Cell differentiation during plant reproduction, genomics and gene regulatory networks, single-cell RNA-sequencing, reprogramming cell fate
Transcriptional and epigenetic mechanisms regulating preimplantation development, pluripotency, differentiation and cellular reprogramming in humans
Environmental and ecological influences on development, reproduction,
and aging in wildlife and humans.
Epigenetic regulation in the context of development and cancer. We focus on heterochromatin and primarily use zebrafish as a model system.
Investigating the regulatory mechanisms of glycosylation using genomic, chemical, and genetic approaches with particular focus on the discovery of novel drugs and targets to treat human diseases.
Behavioral and evolutionary genetics and epigenetics of social insects.
