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Category: Structural Biology

Ramirez, Ana S.

Ana Ramirez

Ana S. Ramirez

Assistant Professor
Biochemistry & Molecular Biology

Structural and mechanistic investigation of the GPI-anchor biosynthesis pathway

Perez, Camilo

Camilo_Perez

Camilo Perez

Assistant Professor
Biochemistry & Molecular Biology

Our research aims to elucidate the mechanism of membrane transporters, flippases, and polymerases involved in bacterial cell wall biosynthesis, unravel how their function influences bacterial adaptation, discover inhibitory molecules for the development of new antimicrobials, and repurpose the activity of these proteins for applications in the synthesis of glycoconjugates. Our lab uses a multidisciplinary approach, combing techniques such as single-particle cryo-electron microscopy (cryo-EM), x-ray crystallography, live cell assays, and various buichemical/biophysical methods to study the function and molecular mechanism of membrane proteins.

 

Website

Wang, Yifan

Yifan Wang

Yifan Wang

Assistant Professor
Chemistry

Catalytic mechanisms and structure-function correlations of metalloenzymes; biomedically essential oxygenases

Website

Barb, Adam W.

Adam Barb (Christopher Gannon/Iowa State University)

Adam W. Barb

Associate Professor
Biochemistry & Molecular Biology

Our goal is to define the impact of protein post-translational modifications on structure and function in the immune system.

Website

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Urbanowicz, Breeanna

Breeanna Urbanowicz

Breeanna Urbanowicz

Assistant Professor
Biochemistry & Molecular Biology;
Complex Carbohydrate Research Center

Structure and function of enzymes involved in plant polysaccharide biosynthesis and modification with the long term goal to develop pathway engineering or targeted genomics approaches for enhanced production of bio-materials, -products, and -fuels.

Website

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Xie, Zhong-Ru (Paul)

Zhong-Ru (Paul) Xie

Zhong-Ru (Paul) Xie

Assistant Professor
Bioinformatics

Computational drug discovery, simulation model, new computational tools for drug design

Website

Edison, Arthur

Arthur Edison

Arthur Edison

Professor
GRA Eminent Scholar
Biochemistry & Molecular Biology; Genetics

Metabolomics and systems biology of Caenorhabditis elegans using NMR,
mass spec, and computational approaches.

Website

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West, Christopher M.

Christopher M. West

Christopher M. West

Professor
Biochemistry & Molecular Biology

Oxygen- and glycosylation-dependent regulation of polyubiquitin ligases in Dictyostelium and Toxoplasma gondii; Glycobiology of protozoa.

Website

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Phillips, Robert

Robert Phillips

Robert Phillips

Professor
Chemistry; Biochemistry & Molecular Biology

Enzymes involved in amino acid, especially tryptophan, metabolism which may be drug targets for cancer, hypertension and neurodegenerative diseases.

Website

Woods, Robert

Robert Woods

Robert Woods

Professor
Biochemistry & Molecular Biology

Immunological carbohydrate-protein interactions studied by computational simulation and experimental methods.

Website

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