Disease Models & Mechanisms

Disease Models & Mechanisms — Identifying links between genetics and the mechanisms of disease is a complex process.  Nevertheless, this process is critical to advancing our understanding of disease formation and progression as well as identifying ways to detect and treat diseases.  The use of genetically modified organisms to model disease is a powerful tool in this process.  Such models allow for enhanced analysis of the contribution of genes to disease pathology.  These models also allow basic science investigations to be more translatable to humans subjects and the clinic.  Members of this group cover the full range of scientific analyses, from genetically modified organisms to human subjects, with genetic and epigenetic analyses, to model and advance the study of a wide variety of human diseases. View faculty»