University of Georgia
Defining the spatiotemporal regulation of kinase pathways and the regulation of GPCR induced inflammation and proangiogenic signaling, for the development of therapeutic agents.
Effects of pathological stress on cells of the peripheral nervous system and the adrenal gland. In vitro disease modeling using human pluripotent stem cells.
Human fungal pathogens, sexual reproduction and development in fungal pathogenesis
Regeneration and development; understanding cellular/molecular mechanisms that underlie neural regeneration in planarians.
The discovery and development of new drugs to prevent or treat malaria and diseases caused by brain-eating amoebae. Elucidating mechanism(s) of resistance and discovering new drug treatment regimens, combinations, or strategies to overcome resistance.
Our research is aimed at identifying the principles of neural circuit assembly, which is key to understanding the treatment of neurological disorders. To achieve this, we develop imaging toolkits including fluorescent probes and advanced microscopes. Website
Toxoplasma’s Strategies to Manipulate Host Immunity
Investigating the regulatory mechanisms of glycosylation using genomic, chemical, and genetic approaches with particular focus on the discovery of novel drugs and targets to treat human diseases.
Role of glycosylation in regulating Notch signaling, assisting protein folding, and development.
Genetic analysis of mouse development; cell fate specification in the embryonic
central nervous system; patterning of the body plan’s left-right axis.
