University of Georgia
Genetic analysis of mouse development; cell fate specification in the embryonic
central nervous system; patterning of the body plan’s left-right axis.
Mammalian germ cell and early embryonic development; meiotic chromosome segregation in oocytes;
genomic instability; impact of age and environment on meiotic division.
We are developing stem cell approaches to repairing bone and nerve injury in addition to
use of stem cells as a tool to screen toxins and potential drug therapies.
Cell Biology of Cilia; Cilia-related diseases, Intracellular Transport.
Post-translational modification including protein acylation, fatty acid metabolism,
prostate stem cell, Src family kinases, prostate cancer, small molecular inhibitor.
Molecular and cellular biology of the human malaria parasite, Plasmodium falciparum.
X-ray crystallographic and biochemical studies of nucleotide sugar metabolism.
We study CRISPR-Cas immune systems that protect prokaryotes from viruses and provide
powerful research tools for important biotechnology and biomedical applications.
Bacterial modulation of eukaryotic membrane dynamics for intracellular survival;
SNARE-dependent membrane fusion biochemistry.
