University of Georgia
We use the advanced genetic mouse models to study the molecular and cellular mechanisms underlying
several diseases: obesity, diabetics, muscle and heart diseases.
Defining the spatiotemporal regulation of kinase pathways and the regulation of GPCR induced
inflammation and proangiogenic signaling, for the development of therapeutic agents.
Effects of pathological stress on cells of the peripheral nervous system and the adrenal gland. In vitro disease modeling using human pluripotent stem cells.
Human fungal pathogens, sexual reproduction and development in fungal pathogenesis
Regeneration and development; understanding cellular/molecular mechanisms that underlie neural regeneration in planarians.
The discovery and development of new drugs to prevent or treat malaria and diseases
caused by brain-eating amoebae. Elucidating mechanism(s) of resistance
and discovering new drug treatment regimens, combinations, or strategies to overcome resistance.
Our research is aimed at identifying the principles of neural circuit assembly, which is key to understanding the treatment of neurological disorders. To achieve this, we develop imaging toolkits including fluorescent probes and advanced microscopes. Website
Toxoplasma’s Strategies to Manipulate Host Immunity
Investigating the regulatory mechanisms of glycosylation using genomic, chemical, and genetic approaches with particular focus on the discovery of novel drugs and targets to treat human diseases.
Role of glycosylation in regulating Notch signaling, assisting protein folding, and development.
