University of Georgia
Vaccine development for prevention of PCP and COPD, RSV infection, COPD; Immunce activation and aging, PAH; Immune-mediated mechanisms of pathogenesis, Type 2 diabetes and metabolic syndrom, therapeuric testing; chronic immune activation/inflammation.
Interactions between microbial pathogens and host immunity in the
mouse model using bacteria that naturally infect mice and
closely related strains that are important human pathogens.
The discovery and development of new drugs to prevent or treat malaria and diseases
caused by brain-eating amoebae. Elucidating mechanism(s) of resistance
and discovering new drug treatment regimens, combinations, or strategies to overcome resistance.
Disease intervention strategies for important human pathogens and emerging infectious diseases of zoonotic origin;
mechanisms of immunity; virus-host interface.
Characterizing the assembly of bacterial surface structures, Development of vaccines for viral
and bacterial pathogens, Systems approaches to understanding microbial diseases
The ecology and evolution of infectious diseases, including measles, pertussis, avian influenza, dengue and polio using computational modeling.
Establishment of the parasite/host niche by filarial worms, specifically Brugia malayi, one of the causative agents of lymphatic filariasis.
Arenavirus glycoprotein structure and function; virus entry and membrane fusion; emerging virus-host interactions. Functional characterization of viral glycoproteins and host interactions.
Veterinary diagnostics; emerging clinical problems; antibiotic resistance;
epidemiology of diseases with special emphasis in zoonoses.
